Product name: Lurasi-done

Cas NO.: 367514-87-2

M.F: C28H36N4O2S

M.W.: 492.68

Capacity: 200KG/M

Usage: Central nervous system 


■ Description

Test ItemsSpecificationsTest Results
Appearancewhite powderLight yellow  powder
Loss on drying≤ 0.5%0.15%
 Single impurity≤ 0.5%0.21%
Total impurity≤ 1.0%0.70%
(By HPLC) PurityNot less than 99%99.30%

General: cas 367514-87-2 lurasidon base is an atypical antipsychotic, and the exact mechanism for treating schizophrenia remains as unclear as other atypical antipsychotics and may be related to the antagonism of dopamine D2 and 5 serotonin 2A (5-HT 2 A) receptors. It is used for the treatment of schizophrenia, and some studies have reported that lur asidone can improve cognitive function.  The hcl salt lurasidon is API also large stock.


Product introduceLur-asidone is suitable for the treatment of schizophrenia. Lurasdone is an antagonist of dopamine D2 and 5-HT7, with IC50 values of 1.68 and 0.495 nM, respectively and is also a partial agonist of 5-HT1A receptor with IC50 value of 6.75 nM.


FunctionLurasidon is used to treat mental illness. Many clinical trials show that it can improve psychotic symptoms, emotional symptoms and cognitive symptoms of schizophrenia patients, and has the safety advantages of little influence on glucose and lipid metabolism indexes and prolactin.


OriginLurasidon is an atypical antipsychotic drug developed by Dainippon Sumitomo Pharmaceutical Company of Japan. On October 28th, 2010, the US Food and Drug Administration (FDA) approved its marketing under the trade name for the treatment of schizophrenia.

■ Message