Product name: Noopept

Cas NO: 157115-85-0

M.F: C17H22N2O4

M.W:318.37

Capacity: 300KG/M

UsageSupplements

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■ Description

NooglutilexhibitspharmacologicallysignificantcompetitionwithaselectiveagonistofAMPAreceptors([G-3H]Ro48-8587)forthereceptorbindingsites(withIC50=6.4+/-0.2microM),whilethecompetitionofnoopeptforthesereceptorbindingsiteswaslowerbyanorderofmagnitude(IC50=80+/-5.6microM)[1].GVS-111significantlyincreasedneurChemicalbookonalsurvivalafterH(2)O(2)-treatmentdisplayingadose-dependentneuroprotectiveactivityfrom10nMto100microM,andanIC(50)valueof1.21+/-0.07microM.GVS-111inhibitedtheaccumulationofintracellularfreeradicalsandlipidperoxidationdamageinneuronstreatedwithH(2)O(2)orFeSO(4),suggestinganantioxidantmechanismofaction[2].

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