Product name: 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
Cas NO.: 881386-01-2
M..F: C11H10Cl2N2O3
M.W.: 289.11
Capacity: 1200KG/M
Usage: apixabn intermediates
■ Description
Apixabn intermediates, intermediates of 503612-47-3.
3,3-Dichloro-1-(4-nitrophenyl)-2-piperidone is an important pharmaceutical intermediate, such as it can be used to prepare apixabn derivatives. Apixabn is a small molecule selective FXa inhibitor of pyrazole derivatives. It has two binding sites for factor Xa, the 4-methoxyphenyl part in the structure of apixabn binds to the pocket of factor Xa, and the aryl lactam part binds to Xa The pocket of the factor.
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