Product name: 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one

Cas NO.: 881386-01-2

M..F: C11H10Cl2N2O3

M.W.: 289.11

Capacity: 1200KG/M

Usage: apixabn intermediates



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■ Description

Apixabn intermediates, intermediates of 503612-47-3.

3,3-Dichloro-1-(4-nitrophenyl)-2-piperidone is an important pharmaceutical intermediate, such as it can be used to prepare apixabn derivatives. Apixabn is a small molecule selective FXa inhibitor of pyrazole derivatives. It has two binding sites for factor Xa, the 4-methoxyphenyl part in the structure of apixabn binds to the pocket of factor Xa, and the aryl lactam part binds to Xa The pocket of the factor.


Product nameCas No.
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate473927-63-8
Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester27143-07-3
3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one88138-01-2
3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one536760-29-9
3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one503615-03-0
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone1267610-26-3
3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one545445-44-1
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester503614-91-3
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate503615-07-4
ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate536759-91-8

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