Product name: 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester

Cas NO.: 503614-91-3

M.F: C27H28N4O5

M.W.: 488.54

Capacity:1200KG/M

Usage: apixabn intermediates

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■ Description

Apixabn intermediates, intermediates of 503612-47-3.


Product introduce: 1-4-Methoxypheny1)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-

Tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester is an intermediate for preparing apixabn, which is an antithrombotic drug. It is a direct inhibitor of factor Xa jointly developed by Bristol-Myers Squibb and Pfizer. It was approved for marketing in the European Union in March 2011 and approved for marketing in the United States by the FDA in December 2012.


Product nameCas No.
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate473927-63-8
Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester27143-07-3
3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one88138-01-2
3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one536760-29-9
3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one503615-03-0
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone1267610-26-3
3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one545445-44-1
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester503614-91-3
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate503615-07-4
ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate536759-91-8

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