Product name:   4-[1-[3-(cyanomethyl)-1-(ethylsulfonyl)-3-azetidinyl]-1H-pyrazol-4-yl]-7H-Pyrrolo[2,3-d]pyrimidine-7-carboxylic acid 1,1-dimethylethyl ester

Cas NO.: 2055723-13-0

M.F: C21H25N7O4S

M.W.: 471.53

Capacity: 1200KG/M

Usage: Baricitinib intermediate

Key intermediate for not patent ros of Baricitinib


■ Description

Cas NO.: 2055723-13-0, this route used for Baricitinib is to be different from patent route (which still valid for at least 5 years). 

To control the single impurity 0.1% of Baricitinib, it better controls it in the crucial baricitinib intermediate. The impurity in 2055723-13-0 is really hard to reduce in later steps (there is method  reducing yet it yeilds less and costs more. very complex ).

We have stock of the intermediate and supplied to Egypt Big group EVA pharm. Any need, pls contact.

Product nameCas No.
4-Pyrazoleboronic acid pinacol ester269410-08-4
tert-butyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate1236033-21-8
3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-1919837-50-5
4-[1-[3-(cyanomethyl)-1-(ethylsulfonyl)-3-azetidinyl]-1H-pyrazol-4-yl]-7H-Pyrrolo[2,3-d]pyrimidine-7-carboxylic acid 1,1-dimethylethyl ester2055723-13-0

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